Ketamine Infusion Therapy | University Pain Consultants
University Pain Consultants  ·  Advanced Therapies

Ketamine
Infusion Therapy

A scientifically validated, physician-supervised treatment for chronic pain and mood disorders — administered personally by our board-certified anesthesiologist, who has worked with ketamine throughout an entire career in anesthesia.

Book Your Consultation — $95
Board-Certified Anesthesiologist

Ketamine has been a core tool of anesthesia practice for decades. Our physician brings that deep clinical expertise to every infusion — this is not a medication we are learning. Every session is personally directed and monitored by the physician.

Getting Started

Begin With a Consultation

Your journey starts with a thorough one-on-one evaluation with our physician to determine whether ketamine infusion therapy is safe and appropriate for you. The $95 consultation fee is credited in full toward your treatment if you proceed.

1
Complete Medical History Review

A thorough review of your diagnoses, prior treatments, current medications, and response to therapies to date.

2
Safety Screening & Candidacy Evaluation

We screen for absolute and relative contraindications — cardiac status, psychiatric history, and any factors that affect your protocol or eligibility.

3
Personalized Treatment Plan

We discuss your individualized dosing protocol, recommended number of sessions, scheduling, and what to expect during each infusion.

4
Full Q&A & Informed Consent

All questions answered before treatment begins. We believe every patient should fully understand each step of their care before proceeding.

Initial Consultation

A private, unhurried evaluation directly with the physician who will administer your treatment. No staff intermediaries. Most consultations take 45–60 minutes.

$95
Credited toward your treatment cost if you proceed. Your consultation fee is never lost.

We give you an honest, thorough assessment — including telling you clearly if ketamine therapy is not right for your situation.

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The Science

How Ketamine Works

Ketamine works through an entirely different biological mechanism than conventional pain medications and antidepressants — which is exactly why it helps patients for whom other treatments have failed.

01

NMDA Receptor Blockade

Ketamine blocks NMDA glutamate receptors in the brain and spinal cord, interrupting the abnormal pain signaling pathways that become hard-wired in chronic pain conditions.

02

Rapid Neuroplasticity

Ketamine rapidly stimulates regrowth of synaptic connections in the prefrontal cortex and limbic system — brain regions that atrophy under chronic pain and depression.

03

Central Sensitization Reset

In chronic pain, the CNS becomes hypersensitized — amplifying pain far beyond its source. Ketamine resets this central sensitization, reducing the overall gain on the pain system.

04

Anti-Inflammatory Action

Ketamine modulates neuroinflammation by reducing pro-inflammatory cytokines in the central nervous system — a key driver of both chronic pain and treatment-resistant depression.

05

Opioid System Interaction

Ketamine interacts with opioid receptors as a partial agonist and can reduce opioid tolerance — making it valuable in opioid-dependent pain patients and opioid-sparing strategies.

06

Faster Than Antidepressants

Conventional antidepressants target serotonin and take weeks to work. Ketamine acts on the glutamate system and can produce measurable mood improvement within 24–48 hours.

Conditions We Treat

Who Ketamine Therapy Helps

Ketamine infusion therapy has clinical evidence for a wide range of pain and mood disorders. Below are the conditions with the strongest support.

Complex Regional Pain Syndrome (CRPS)

Among the strongest evidence bases for ketamine — Type I & II refractory to other treatments.

Treatment-Resistant Depression

For patients who have failed two or more antidepressant trials. Rapid response within 24–72 hours.

Fibromyalgia

Addresses central sensitization underlying widespread pain, fatigue, and cognitive symptoms.

Chronic Pain Syndrome

Centrally mediated chronic pain that has not responded to conventional treatment approaches.

Chronic Neuropathic Pain

Peripheral neuropathy, diabetic neuropathy, post-herpetic neuralgia, and other neuropathic syndromes.

Spinal Pain

Failed back surgery syndrome, chronic radiculopathy, and refractory axial low back pain.

Post-Traumatic Stress Disorder (PTSD)

Emerging strong evidence for reduction of PTSD symptom severity, hyperarousal, and trauma-related pain.

Chronic Migraine & Cluster Headache

For intractable migraines and cluster headache cycles unresponsive to conventional preventive therapies.

Phantom Limb Pain

Central pain mechanisms driving phantom limb pain respond to NMDA blockade, with documented improvement.

Acute Suicidal Ideation

Rapid reduction of acute suicidal ideation as an adjunct to standard care — FDA-recognized via esketamine pathway.

Obsessive-Compulsive Disorder

Preliminary but promising evidence for rapid antiobsessional effects in treatment-refractory OCD.

Safety Profile

Potential Side Effects

At the sub-anesthetic doses used in infusion therapy, ketamine has a well-established safety record. Side effects are almost always transient and resolve within minutes to hours after the infusion ends.

During Infusion

Dissociation / Dreamlike State

During Infusion

Mild Perceptual Changes

Transient

Nausea

Transient

Dizziness or Lightheadedness

Transient

Elevated Blood Pressure & Heart Rate

Transient

Blurred or Double Vision

Transient

Headache

Rare

Anxiety or Agitation

Post-Infusion

Fatigue or Drowsiness

Rare

Vivid Dreams

A Note on Safety: Because our infusions are administered and monitored by a board-certified anesthesiologist who has used ketamine routinely in the operating room throughout a career, the risk of adverse events is substantially lower than in clinics staffed by non-anesthesiologist providers. We are equipped and trained to manage any eventuality before it becomes a problem.

Patient Safety

Contraindications

Ketamine is not appropriate for everyone. A thorough medical screening at consultation identifies patients for whom treatment is either absolutely contraindicated or requires careful individualized risk-benefit evaluation.

Condition Classification Clinical Rationale
Schizophrenia or Schizoaffective DisorderAbsoluteKetamine can precipitate or worsen psychosis; NMDA blockade mimics schizophrenia-like symptoms
Uncontrolled HypertensionAbsoluteKetamine reliably raises blood pressure; risk of hypertensive crisis in uncontrolled hypertension
Active Mania or Bipolar I (Manic Phase)AbsoluteRisk of precipitating or exacerbating a manic episode
Recent Myocardial Infarction (<6 months)AbsoluteCardiovascular stimulation poses unacceptable risk to recently injured myocardium
Elevated Intracranial PressureAbsoluteKetamine can further raise ICP in patients with space-occupying lesions or hydrocephalus
Active Stimulant or Dissociative Substance Use DisorderAbsoluteRisk of misuse, unpredictable pharmacological interactions, and diversion
PregnancyAbsoluteInsufficient safety data; potential teratogenic and neurodevelopmental risk to fetus
Unstable Coronary Artery Disease / AnginaRelativeCardiac stimulation may trigger ischemia; may proceed with cardiologist clearance and close monitoring
History of Psychosis (in remission)RelativeCase-by-case evaluation; may proceed with psychiatric co-management in stable patients
Severe Hepatic InsufficiencyRelativeKetamine is hepatically metabolized; may accumulate unpredictably in severe liver disease
Hyperthyroidism (uncontrolled)RelativeExaggerated sympathomimetic response; thyroid disease should be treated and controlled first
Poorly Controlled Seizure DisorderRelativeConflicting data on seizure threshold; may proceed only if epilepsy is well-controlled and neurology consulted
Your Experience

What to Expect

We work hard to make every infusion safe, comfortable, and as positive an experience as possible.

Before Your Infusion

Fast for 4–6 hours before treatment. Arrange a driver — you will not be permitted to drive yourself home. Wear comfortable clothing. You may bring headphones and a personal playlist; many patients find music significantly enhances their experience.

During Your Infusion

You will recline comfortably in a private, dimly lit room. An IV is placed and the infusion runs over 40–60 minutes (pain protocols) or 2–4 hours (ultra-low-dose protocols). Vital signs are monitored continuously throughout.

The Ketamine Experience

At sub-anesthetic doses you remain conscious and able to communicate. Most patients describe a dreamlike, floating sensation with gently altered perception of time and space. This resolves fully within minutes of the infusion ending.

Recovery & Discharge

You may rest in our recovery area for 30–60 minutes post-infusion. Once you meet discharge criteria — stable gait, normal vitals, no nausea — you are released to your driver. Most patients feel well enough for light activity the same evening.

When Will I Feel Better?

Pain relief can begin within 24–72 hours of the first infusion for some patients. Mood improvement is often even faster. Results accumulate across a series — most patients experience the greatest benefit after completing 4–6 sessions.

Maintenance & Follow-Up

After your initial series, many patients require periodic maintenance infusions — monthly to quarterly — to sustain their response. We create a long-term plan tailored to your individual needs and response to treatment.

Your Journey

The Treatment Process

1

Consultation

Physician evaluation & candidacy screening

2

Protocol Design

Personalized dosing & scheduling plan

3

Infusion Series

4–6 sessions over 2–3 weeks

4

Response Assessment

Objective evaluation of your outcomes

5

Maintenance Plan

Ongoing care to sustain your results

Transparent Pricing

Investment in Your Recovery

We believe in clear, honest pricing with no hidden fees. Insurance does not typically cover ketamine infusion therapy, so we offer a meaningful discount when committing to the recommended initial series.

Single Session

$700
per infusion session
  • Physician-administered infusion
  • Continuous vital sign monitoring
  • Private infusion suite
  • Recovery period included
  • Post-infusion physician check

HSA/FSA cards accepted · Financing options available — ask at consultation

Ready to Explore a New Path Forward?

Schedule your consultation today. Most appointments are available within 1–2 weeks.

Schedule My $95 Consultation

Medical Disclaimer: Ketamine infusion therapy is an off-label use of an FDA-approved medication for most indications listed. Results vary between individuals and are not guaranteed. This page is for informational purposes only and does not constitute medical advice. Candidacy is determined on an individual basis following a complete medical evaluation. Ketamine is a Schedule III controlled substance administered only under direct physician supervision in a licensed clinical setting. These services are not covered by insurance in most cases; patients are responsible for the full cost of treatment.